Covid19 and long covid: possible sequelae on the organism (even "mild" cases)

[Christophe]

And the essence of the 2nd article:

Cellular receptors and proteins under the microscope

To carry out this study, researchers specializing in molecular biology, genetics and biotechnology tracked down the cellular factors that could play a role in infection with the coronavirus.
They mainly relied on 28 genes which contain the information necessary to manufacture three types of factors:

- receptors present on the surface of cells (or cellular receptors) which allow the virus to cling to and penetrate them, such as the famous ACE2 receptor;
- proteins present in cells, which the virus needs to multiply;
- proteins which, on the contrary, block the penetration of the virus into cells.

A "battlefield" in the nose

Once these 28 genes were identified, they studied their activity in around 400.000 human cells from different types of tissues: nasal mucosa, lungs, intestine, brain, male and female reproductive organs and even the placenta. Their results provide a map of potentially disease-related factors throughout the human body.

First sensitive area, which the researchers qualify as a "battlefield": the nasal mucosa, where cells present both factors that facilitate infection (such as the ACE2 receptor) and others that inhibit the entry of the virus . "It therefore seems that the contact of the virus with the nasal mucosa leads to a tug-of-war. The question then becomes who will be the winner" comments Dr. Vikas Bansal, co-author of the study, in a press release from the DZNE .

Interestingly, "the level of expression of entry factors in human nasal tissue changes with age," he also specifies. "This could be a reason why the elderly are more likely to be infected with the CoV-2 of SARS", interprets the researcher.
Multiple entry doors

But the virus is not limited to the upper respiratory tract. According to the researchers, the intestines, kidneys, testes and placenta are potential sensitive areas because these organs have both cell receptors and proteins that facilitate the entry of the virus into cells.
Cellular receptors facilitating the entry of SARS-CoV-2 are also observed in the lungs, the heart, and the central nervous system, namely the brain and the spinal cord.

covid-cells-organs3.jpg (309.34 KiB) Viewed 2499 times

Representation of the different target organs of SARS-CoV-2 and cells specific to each organ carrying receptors facilitating the passage of the virus. Diagram inspired by the figure presented by Singh et al. 2020. https://doi.org/10.1016/j.celrep.2020.108175.

[Obamot]

And doing all that, it would be a virus ”natural"

[Christophe]

I think that he is more natural than islamist !

[Obamot]

Neither is it possible?

3 days ago, the virologist E. Decroly. specialist in emerging viruses at the CNRS, did not rule out the thesis of 'the accident' laboratory!

https://www.lci.fr/international/covid-19-et-si-le-pangolin-n-etait-pas-a-l-origine-de-la-transmission-du-virus-2168679.html

[Christophe]

Subject gourage !!

[Christophe]

To be taken with a grain of salt ...

Affected by coronavirus at 16 weeks pregnant, this caregiver is now fighting cervical cancer

https://www.sudinfo.be/id275301/article ... ante-lutte

[Obamot]

It is not so surprising that someone borderline to the point of having had cancer - which proves a weakening of their immune defenses - this mugs the coronavirus ... (Even if the cancer is revealed late, if we did a biocheck for him, I wouldn't be surprised if many of the counters of his impairments were in crimson red ... But I sympathize with his suffering, it must be terrible to realize that I have both simultaneously, I think. strong to her )

She's lucky to have survived the covid, that's already it ...

[Janic]

She's lucky to have survived the covid, that's already it ...

if it's to die of cancer, I don't see the benefit!

[Christophe]

[Christophe]

Above all, let's not change anything ... let's continue to make a policy solely based on deaths and the saturation of hospitals !!!



To be compared with MASSIVE contaminations of young people: health-pollution-prevention / my-wife-works-in-a-school-t16542-20.html # p418881

COVID-19: asymptomatic form could damage the heart

The new coronavirus can cause severe acute respiratory infection, but also heart damage. The latter were the subject of an American study, the results of which were published in JAMA Cardiology.

Heart abnormalities in student athletes

The study carried out by American cardiologists highlights a potentially dangerous impact, on the cardiovascular system, in young students, who have presented with an asymptomatic or mild form of Covid-19. For this research, cardiac imaging exams were performed on 54 student-athletes, with an average age of 19, at the University of West Virginia. These young people have tested positive three to five weeks earlier. Scientists noticed inflammation of the heart and excess fluid in the pericardium (the membrane that surrounds the heart), but no "continued damage to the heart muscle." The Sars-Cov-2 virus could be responsible for triggering inflammatory responses in the heart, as the body fights against the pathogen. For 48 young athletes who passed the two exams, “abnormal results were identified in 27 people”, or 56,33%. The researchers wanted to know if the virus could enter the heart muscle. Their study did not reach this conclusion, but it still revealed the appearance of signs of inflammation of the pericardium (pericarditis).

Precautions for these students

In fact, 40% of the student-athletes screened presented with pericarditis, while 58% of them had pericarditis effusion. This build-up of fluid in the heart muscle is usually mild and can heal within a few weeks without causing long-term consequences. However, in some cases, it can cause recurrent inflamed pericarditis. Researchers insist on quarantine as soon as a student tests positive for Covid-19. They recommend determining on a case-by-case basis whether cardiac examinations are useful. Regarding athletes showing signs of myocarditis, the team recommends that young people avoid competing in sports or intense training for a period of three to six months. She also advises to consult a cardiologist in order to take examinations and to be monitored as part of a gradual return to sport. On the other hand, scientists advise against sport for athletes suffering from pericarditis. As physical activity can exacerbate inflammation, it is better, according to them, to wait for its complete disappearance, proven by conclusive cardiac examinations, before resuming training.

Fortunately, at home, young people, it is rather benign ...

https://www.passeportsante.net/fr/Actua ... -leser-cur