Glyphosate: an effective ecological herbicide, not carcinogenic, not endocrine disrupting

[ABC2019]

Guitounet has done all the expertise in his garden, and he is categorical: it is a powerful neurotoxicant. We can see the result ...

[GuyGadeboisTheBack]

Summary of two recent scientific studies (2020 and 2021) and NOT the stupid, sordid and absolutely WITHOUT ANY IMPORTANCE OR REACH of a stupid jerk in the pay of his billionaire boss .....

The team of researchers from the University of Birmingham wanted to quantify the impact of glyphosate on an animal model often used in ecotoxicology: daphnia. The interest of this crustacean, a common species in freshwater habitats, is that it occupies a central position in the food chain of aquatic ecosystems. Thus, understanding the impact of the weedkiller on this species informs us of possible cascading effects on aquatic food webs and on the disruption of essential services provided by freshwater ecosystems.

Chronic exposure to glyphosate and its commercial formula, Roundup, at the maximum level allowed in drinking water in the United States, has been found to have serious adverse effects on daphnia. Indeed, embryonic development disorders and a genotoxic effect have been observed in this non-target aquatic invertebrate. The impact of exposure to sublethal (i.e. lower than the lethal dose) concentrations of Roundup and glyphosate has already been shown in other non-target species such as fish. zebra. The observed effects range from a low hatching rate to embryo mortality and developmental abnormalities. Genotoxicity has been demonstrated in other species, including human cell lines.
This study shows that early exposure to pollutants has a strong impact on the dynamics, establishment and function of the microbiome, which has been observed in other species (eg, mice). The results also indicate that glyphosate and Roundup had a significant impact on scanty intestinal bacterial taxa, which were severely affected in established communities. However, the latter are the main factors in the composition of communities and, therefore, are particularly important for the function of the microbiota. Indeed, the changes in these taxa caused by exposure to glyphosate and Roundup, at doses well below the accepted regulatory toxicity thresholds, have contributed to significant alterations in the main functional pathways.

The study describes changes in Actinobacteria, a family of bacteria abundant in a wide range of aquatic and terrestrial environments and which notably plays a key role in the homeostasis of the human intestine. Disruption (dysbiosis) of the gut microbiota linked to actinobacteria has been associated not only with intestinal disorders, but also with many extra-intestinal diseases such as metabolic and neurological disorders. This bacterial group is so important that probiotic supplements containing Actinobacteria are used to improve the health of the gut microbiota in the prevention of degenerative diseases, such as obesity, diabetes, cancer, cardiovascular disease, liver disease and inflammatory bowel disease.

Another team of European researchers has studied the toxic effects of glyphosate on the intestinal microbiota and the serum metabolome of rats, via a multi-omics approach. The results highlight changes in metabolite levels, suggesting that glyphosate inhibits the shikimate pathway in the rat gut microbiome. Although the latter is significantly different from that of humans, the researchers believe their findings will be relevant to human physiology, as it has been found that the bacterial species that live in the human gastrointestinal tract are sensitive to it. glyphosate-mediated EPSPS inhibition. However, epidemiological studies will be needed to determine whether the doses of glyphosate to which human populations are generally exposed are sufficient to alter the metabolism of the gut microbiomes.

In addition, many studies have reported that commercially formulated pesticide products are more toxic than their sole active ingredient. This has been demonstrated repeatedly for glyphosate herbicides and also for other classes of pesticides such as insecticides or fungicides. This difference in toxic effects is usually due to the toxicity of the surfactants and other compounds that make up the admixture of adjuvants in commercial pesticide formulations, although it cannot be ruled out that these surfactants may as well. potentiate the penetration of glyphosate into the tissues. Here, serum metabolomics suggested that the glyphosate-based formulation had a greater impact than the pesticide alone on the serum metabolome, indicating systemic toxic effects. However, it should be noted that the results show limited effects of these co-formulants compared to glyphosate, which was the main cause of the metabolic changes observed.

In summary, the first study presented shows that chronic exposure to concentrations of Roundup and glyphosate well below the approved regulatory threshold causes failure of embryonic development and alteration of metabolic pathways through a direct effect on the host and an effect indirect on the intestinal microbiota in daphnia. As daphnia is at the heart of the aquatic ecosystem food chain and is an indicator of ecosystem health, the weedkiller has the potential to significantly impact freshwater aquatic food chains, affecting their ability to provide services. essential ecosystems (eg clean water, nutrient cycling).

https://www.generations-futures.fr/actu ... t-nefaste/
Scientific sources:
(Translated: https://translate.google.com/translate? ... 20-00943-5 )
(Not translated: https://ehp.niehs.nih.gov/doi/10.1289/EHP6990 )

[izentrop]

chronic exposure to glyphosate and its commercial formula, Roundup, at the maximum level permitted in drinking water in the United States, has serious adverse effects on daphnia.

This does not concern Europe or the much lower doses (no roundup ready), no roundup either in agriculture and spreading rules avoiding the contamination of waterways.

However, epidemiological studies will be needed to determine whether the doses of glyphosate to which human populations are generally exposed are sufficient to alter the metabolism of the gut microbiomes.

Given the doses used, they must know.
This kind of sentence, it's just to titillate people who are looking for the little beast like Veillerette or the guys with wooden heads

[Janic]

hugh! Mr. Rondup has spoken!

[GuyGadeboisTheBack]

hugh! Mr. Rondup has spoken!

Mr. Roundup who is a renowned scientist, an informed toxicologist who swallows everything that the AFIS, FSNSEA, L'Express and the World swings at ... and who sweeps away with the back of his hand contemptuous of the real specialists who work on this without being sponsored by Monsanto / Bayer (ex IG Farben, the chemical Nazis). Pathetic. Lack more than Blédina to complete the picture but we can bet that he will also come to play "Monsieur Plus de Bayer" to give a little boost to this deadly industry.

[Exnihiloest]

blabla ...

All scientific studies have shown that glyphosate is an ecological, non-carcinogenic and non-endocrine disrupting herbicide (glyphosate, not Round-up).

This is why it is used almost everywhere in the world, except in Europe for individuals, the green lobby and ecofascism having been there.
This is also why its detractors here are unable to present us with a scientific consensus against glyphosate.

It is that its detractors, either act in the movement of obscurantism, and claim everything that is artificial is bad since it is unnatural, or in the anti-capitalist political movement, and claim that everything that is artificial is bad in order to to penalize industry and piss off capitalism.

[GuyGadeboisTheBack]

CQFD, the servile moron of service has raged again. No surprises, ever. Coming from nothing, he embodies nothingness.

[Obamot]

Damn, “ecological” glyphosate when will we see an “BIO” label?

I apologize but to say that is a monumental blunder! A nutty VRP argument

[izentrop]

That's it, the third specialist es-phytos who know much better than the experts in the field has given his opinion. We are saved

[GuyGadeboisTheBack]

The specialists, they are there, my poor Izy, not in your fantasies:
https://translate.google.com/translate? ... 20-00943-5
https://ehp.niehs.nih.gov/doi/10.1289/EHP6990
Nor in an article in Le Monde ...