Angelfish protector / Olm, fountain of youth of humanity?

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Christophe
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Angelfish protector / Olm, fountain of youth of humanity?




by Christophe » 17/06/11, 10:36

Do you know the Proteus (Olm, white salamander, cave salamander ...)? It presents exceptional survival conditions and above all it does not age!

proteus_protee_anguillard.jpg
proteus_protee_anguillard.jpg (123.22 KB) Consulted 7703 times


Another champion of biodiversity, even if it does not do as well as tardigrade:
Science-and-Technology / tardigrade-the-extreme-strength-and-cryptobiosis-t12339.html

Extract from his wiki page: http://fr.wikipedia.org/wiki/Proteus_%28Amphibien%29

When food is scarce, it reduces its activity and its metabolism. It can even reabsorb its own tissues in the most critical cases. Experiments have shown that he can survive up to ten years without food.


The average lifespan of a protea is estimated at around 58 years [25]. Some individuals have nevertheless been kept in artificial tanks in semi-natural conditions for almost 70 years [26].


There is a 2 page article in the latest S&V that details these survivability and anti aging performance, I will scan it.

So "telomerization" (modification of telomeres to slow down aging, or even cancel it ??) soon available thanks to Olm? : Cheesy: : Cheesy:

Not even worth it, it has already been identified:
http://fr.wikipedia.org/wiki/T%C3%A9lom%C3%A8re

In 1971, Russian biologist Alekseï Olovnikov hypothesized for the first time that the maximum lifespan of cells in culture (Hayflick limit) is correlated with the progressive loss of telomeric sequences. Indeed, during each cell division, the telomeres erode until reaching a critical size which then triggers an entry into senescence of the cell. Telomeres act like a biological clock governing the lifespan of cells. This theory is known as the telomeric theory of aging. He also predicted the existence of an enzyme capable of reversing the process by synthesizing new telomeric DNA sequences: it is called telomerase. The identification of telomerase was made in 1985 by Elizabeth Blackburn and Carol Greider [1]. This work was awarded the Nobel Prize in physiology or medicine in 2009.
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phil53
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by phil53 » 17/06/11, 10:51

Yes but in the article in question they also say that she sleeps almost all the time.
So it's more a kind of hibernation than real life.
It's like turtles, they live old but in slow motion.

This does not detract from research on cell aging
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by Christophe » 17/06/11, 10:57

Yes absolutely, it can greatly reduce its metabolism, this explains its long lifespan (well, a classic salamander also has a long lifespan: 20 years in the wild, 50 in captivity!) And its ability not to s 'feeding for extremely long periods, but that does not explain the lack of aging of its cells, it is really this that makes it interesting! (the telomeres hypothesis is not mentioned in the article, only antioxidants ...)

In all cases, it is less "good" than the cryptobiosis of tardigrade (state of apparent death!): https://www.econologie.com/la-cryptobios ... -2745.html : Mrgreen:

(Litt.vie hidden)

Cryptobiosis is a state of suspension of biological activity in which the intensity of internal processes drops to a fraction which can be very small, from its usual level. It is a form of resistance which makes the cryptobiotic animal very resistant to cold, heat and time in particular.

We can consider it as an extreme of hibernation. Nematodes in an encysted state can remain for more than ten years in a dry environment before regaining their worm form, taking advantage of the favorable living conditions that their host provides. Rotifers and some insects and crustaceans are also capable of entering cryptobiosis when the living conditions of their environment become difficult.


As long as we are in the potentially "miraculous" applications of biodiversity, we could also talk about the regenerative capacities of the members of the salamander ...
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dedeleco
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by dedeleco » 17/06/11, 13:43

All living things, bacteria of ours, in difficult conditions, lack of food, caloric restriction, live longer, even us by 20% and more (case of my mother-in-law who always has a good reason for not eating anything ), and flies overwinter as well when they only live a little over a month !!

Natural selection only selects those who survive and therefore those who live long without food, as long as they have not reproduced.
This for more than 3 billion years !!

But the structure of life, of the genetic code is hyper-complex following this evolution, self-adaptive and we still discover surprises with a very complex functioning of the genetic code (the microRNA changes its functioning).

Given this complexity, we must not believe that we will be able to quickly use the capacities of the animals selected in almost unbearable conditions to live long !!
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Re: Protée anguillard / Olm, fountain of youth for humans




by sen-no-sen » 17/06/11, 14:54

Christophe wrote:


So "telomerization" (modification of telomeres to slow down aging, or even cancel it ??) soon available thanks to the Olm? : Cheesy: : Cheesy:



Ah the old dream of immortality!
But what would it be for?
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Re: Protée anguillard / Olm, fountain of youth for humans




by Christophe » 17/06/11, 15:04

sen-no-sen wrote:Ah the old dream of immortality!
But what would it be for?


Good question ! Attention it is not a question of immortality but of slowing down of aging ... there is still a (sacred) difference! Not sure that the human spirit can bear to be 1000 years in the same body ...

The benefits of limiting aging?

Live your whole life in good / better health.
Being able to perform longer (25 years is the pinnacle for the brain)
Being able to choose when you want to leave ...

Etc., etc...

After it is known that there is no more "unnatural" as a practice, GMOs next to it is a CP experience ...

So the question is more in the field of philosophy and ethics than health ... anyway, we are not there yet ... : Cheesy:
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by dedeleco » 17/06/11, 15:10

Calorie restriction works on humans !!

10 to 20 %% with statistical certainty !!

See my mother-in-law as an example compared to her brother, 41 years older !!
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by Christophe » 17/06/11, 15:12

dedeleco wrote:See my mother-in-law as an example compared to her brother, 41 years older !!


Ben shows there !!! We don't know her! : Cheesy:

41 years of difference between them?
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by dedeleco » 17/06/11, 15:19

50 years since he died while being a little older, but very fat and very good living !! !!

She with a hiatal hernia with an instantly filled stomach and is the opposite of her brother !!!
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Re: Protée anguillard / Olm, fountain of youth for humans




by sen-no-sen » 17/06/11, 15:31

Christophe wrote:
sen-no-sen wrote:Ah the old dream of immortality!
But what would it be for?


Good question ! Attention it is not a question of immortality but of slowing down of aging ... there is still a (sacred) difference! Not sure that the human spirit can bear to be 1000 years in the same body ...



There may not be any question of short-term immortality, but that is strongly implied.
According to some scientists, by 2050, it will be possible to "create" human beings capable of living for more than 200 years ... already we can not pay pensions! : Mrgreen:



Live your whole life in good / better health.
Being able to perform longer (25 years is the pinnacle for the brain)
Being able to choose when you want to leave ...


This, unfortunately, is part of a scientist logic, death being a natural thing and although it does not matter, we will not die!
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