Covid-19. Actemra seems effective

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Covid-19. Actemra seems effective




by ENERC » 27/04/20, 19:20

I already told you about drug tests to block interleukin-6. The idea is to avoid the inflammatory reaction responsible for severe cases.
Coronavirus: Hospitals in Paris are hopeful of finding treatment for severe cases

A state-of-the-art therapeutic trial with a molecule which combats the inflammatory reaction, tocilizumab (marketed by Roche under the name Actemra), shows encouraging results. The hospital group did not wish to reveal the precise results, until they have been approved by the reading committee of the scientific journal which could publish them.

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According to Bruno Lina in today's "C dans l'air" show the results are very interesting.

The demonstration was carried out as part of the Corimuno therapeutic trial, which brings together more than 420 Covid-19 patients and has several "arms" (sarilumab, serum from cured patients, etc.). For 14 days, 129 patients were included in the tocilizumab arm, of which 65 received this molecule marketed by the Roche laboratory under the name Actemra, and 64 were treated in the usual way - oxygen, antibiotics, anticoagulants. All were already on oxygen, a sign of a serious form of the disease. The objective, which was to reduce the risk of going into intensive care and increase the chances of survival, was achieved. But we do not know in what proportions.


This drug, whose injection costs 822 euros, does not present any particular difficulty of supply, also points to the AP-HP
822 € the dose ??

The article is here: https://www.lesechos.fr/economie-france ... es-1198509
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Re: Covid-19. Actemra seems effective




by GuyGadebois » 27/04/20, 19:33

ENERC wrote:
This drug, whose injection costs 822 euros, does not present any particular difficulty of supply, also points to the AP-HP
822 € the dose ??

And yes, when it's expensive *, it works. When it's for nothing, it doesn't matter! What sham. : Evil: (It is of course a randomized double-blind study ... ah no? Ah good ...)

* Associated with oxygen, antibiotics, anticoagulants ... : roll:
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Re: Covid-19. Actemra seems effective




by Christophe » 27/04/20, 23:07

ENERC wrote:reducing the risk of going into intensive care and increasing the chances of survival has been achieved. But we do not know in what proportions.


It's a joke ????

ENERC wrote:
This drug, whose injection costs 822 euros, does not present any particular difficulty of supply, also points to the AP-HP
822 € the dose ??


822 is the price of the box or all that goes around for the injection? That is to say all the medical monitoring ...

If it's the second case it's not so expensive ... : Cheesy:
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Re: Covid-19. Actemra seems effective




by Adrien (ex-nico239) » 27/04/20, 23:54

Here in the present case communicate results without validation by press release, it's good
The wording and its expected vaguely remind me of someone

https://www.lesechos.fr/economie-france ... es-1198509

These hopes have been deemed "communicable" now, because "in the pandemic context", it seemed "ethical" to share them as quickly as possible, explained the director general of the AP-HP, Martin Hirsch.
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Re: Covid-19. Actemra seems effective




by Christophe » 28/04/20, 00:02

Who is that ? : Mrgreen:

The hospital group did not wish to reveal the precise results, until they have been approved by the reading committee of the scientific journal which could publish them.


See you in 4 months?

Polyarthrite rhumatoïde

Other hospitals, such as Foch Hospital in Suresnes, or abroad, have noted for a few weeks the encouraging effects of this molecule, which is usually prescribed in France for 10.000 patients suffering from rheumatoid arthritis.


Hold on like the plaquenil!
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Re: Covid-19. Actemra seems effective




by Adrien (ex-nico239) » 28/04/20, 00:07

Christophe wrote:Who is that ? : Mrgreen:

The hospital group did not wish to reveal the precise results, until they have been approved by the reading committee of the scientific journal which could publish them.


See you in 4 months?

Polyarthrite rhumatoïde

Other hospitals, such as Foch Hospital in Suresnes, or abroad, have noted for a few weeks the encouraging effects of this molecule, which is usually prescribed in France for 10.000 patients suffering from rheumatoid arthritis.


Hold on like the plaquenil!


They announced an accelerated reading ....

And yes like the plaquenil
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Re: Covid-19. Actemra seems effective




by Obamot » 16/06/20, 13:19

GuyGadebois wrote:
ENERC wrote:
This drug, whose injection costs 822 euros, does not present any particular difficulty of supply, also points to the AP-HP
822 € the dose ??

And yes, when it's expensive *, it works. When it's for nothing, it doesn't matter! What sham. : Evil: (It is of course a randomized double-blind study ... ah no? Ah good ...)

* Associated with oxygen, antibiotics, anticoagulants ... : roll:


- “Roche has launched a Phase III study in collaboration with Gilead to evaluate the safety and efficacy of Actemra / RoActemra (tocilizumab) in combination with remdesivir in hospitalized patients with severe COVID-19 pneumonia. "

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Re: Covid-19. Actemra seems effective




by GuyGadebois » 16/06/20, 13:21

Obamot wrote:
- “Roche has launched a Phase III study in collaboration with Gilead to evaluate the safety and efficacy of Actemra / RoActemra (tocilizumab) in combination with remdesivir in hospitalized patients with severe COVID-19 pneumonia. "

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What a dark farce ...
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Re: Covid-19. Actemra seems effective




by Christophe » 16/06/20, 22:24

GuyGadebois wrote:What a dark farce ...


Racist !!

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Re: Covid-19. Actemra seems effective




by GuyGadebois » 16/06/20, 22:43

Christophe wrote:
GuyGadebois wrote:What a dark farce ...


Racist !!

Image

There it is darker, it is murky. : Mrgreen: : Cheesy: :P
There is nothing worse (dick schnell) blind than a creepy man.
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“It is better to mobilize your intelligence on bullshit than to mobilize your bullshit on intelligent things. (J.Rouxel)
"By definition the cause is the product of the effect". (Tryphion)
"360 / 000 / 0,5 is 100 million and not 72 million" (AVC)

 


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