Advances in the fight against the coronavirus

[GuyGadebois]

22 deaths for Redemsivir against 16 for HCQ (out of 158 patients treated), I do not call that "an insignificant difference in mortality", the family of the deaths certainly neither.

[Adrien (ex-nico239)]

The ennobling of Remdesivir was planned

6 June

But I have no illusions Gilead is too strong.
Money flows freely.
And as things go, it is quite possible that Remdesivir will soon become the only politically “valid” treatment to date and even in Africa.

3 June

The non-toxicity of hydroxychloroquine is already a nice concession.
One wonders if at the point where we are we should not negotiate and find (even if it's facade) any interest in the Remdésivir story that Gilead who seems so influential and powerful can come out with his head held high (and his actions with ).

[ABC2019]

The non-toxicity of hydroxychloroquine is already a nice concession.
One wonders if at the point where we are we should not negotiate and find (even if it's facade) any interest in the Remdésivir story that Gilead who seems so influential and powerful can come out with his head held high (and his actions with ).

if giving 4 times the usual dose shows neither toxicity nor efficiency, then it is neither toxic nor effective, right?

[sicetaitsimple]

22 deaths for Redemsivir against 16 for HCQ (out of 158 patients treated), I do not call that "an insignificant difference in mortality", the family of the deaths certainly neither.

It is not me who writes it, but the co-authors of the study including Professor Raoult.

[ABC2019]

22 deaths for Redemsivir against 16 for HCQ (out of 158 patients treated), I do not call that "an insignificant difference in mortality", the family of the deaths certainly neither.

It’s just because you don’t know how to assess the significance of a deviation, have you ever heard of Poisson noise at the root (N)? (no it's not about the noise made by salmon or tuna ...)

https://fr.wikipedia.org/wiki/Loi_de_Poisson

[sicetaitsimple]

This is not really what Professor Raoult and his team wrote in a pre-print posted online yesterday or today on the IHU website, at least concerning lethality.

https://www.mediterranee-infection.com/ ... _final.pdf

If I understood correctly, they made a comparison between the results of Chinese studies and theirs by "extracting" from their cohort of 3000 patients the results of a sample with the same profile (age, gender, progression of symptoms ,, ...) than those of the Chinese study.

Regarding Remdesivir, it is written:

No significant differences in demographic and clinical characteristics were found between the
190 remdesivir group and the HCQ + AZ group. The two groups were thus strictly comparable at
191 baseline. There were no significant differences in death between the two treatments. Sixteen
192 patients (10%) died in the HCQ + AZ group versus 22 (14%) in the remdesivir group (p-value
193 = 0) (Table 30). However, more patients left the hospital cured following HCQ + AZ
194 treatment (123 (78%) versus 92 (58%), p-value = 0 · 0001). The median hospital stay length
195 and median oxygenation duration were shorter

Note that on the other hand (same publication of the IHU) the HCQ + AZT comparison vs lopinavir + ritonavir proves favorable to the HCQ + AZT treatment.

[Obamot]

"The Chinese are starting to gradually release their studies. All show that the drug remdesivir from the Gilead laboratory, on which France has relied heavily, does not work," said Marseille professor Didier Raoult based on a multi-centric study against Placebo. Associating this study with another from the United States, Professor Raoult draws the conclusion that this drug "does not save lives", as it is also ensured by the American study.

https://www.laprovence.com/actu/en-dire ... oquine.htm

With everything we read it looks more and more like a backfire, they knew their molecule lower than bi-HCQ, so they paid for false studies to sink the HCQ?

And it is certain that his lobbies pay pawns on the forums, to make disinformation on all kinds of subjects ...
Suddenly, by reading the contradictory remarks of certain trolls, you say to yourself that there is an eel under the rock ... So some have never participated in a subject to suddenly invest themselves, by posting soothing things, since they only know the subject from afar.

[Adrien (ex-nico239)]

"The Chinese are starting to gradually release their studies. All show that the drug remdesivir from the Gilead laboratory, on which France has relied heavily, does not work," said Marseille professor Didier Raoult based on a multi-centric study against Placebo. Associating this study with another from the United States, Professor Raoult draws the conclusion that this drug "does not save lives", as it is also ensured by the American study.

https://www.laprovence.com/actu/en-dire ... oquine.htm

With everything we read it looks more and more like a backfire, they knew their molecule lower than bi-HCQ, so they paid for false studies to sink the HCQ?

And it is certain that his lobbies pay pawns on the forums, to make disinformation on all kinds of subjects ...
Suddenly, by reading the contradictory remarks of certain trolls, you say to yourself that there is an eel under the rock ... So some have never participated in a subject to suddenly invest themselves, by posting soothing things, since they only know the subject from afar.

Ah well troll lobbyist for failed researcher it is a reconversion like any other

[Christophe]

Powerful antibodies discovered in the Netherlands in patients cured of coronavirus

Researchers at the University of Amsterdam have identified two proteins that show promise in the treatment of coronavirus. These antibodies come from the blood of patients who have been cured of Covid-19.

Researchers at UMC Amsterdam have isolated the two most potent antibodies. The results were published Monday in the journal Science.

"These new antibodies are a hundred times more powerful", according to the head of research, Dr Marit van Gils. "We tested all the antibodies in the blood in the lab and isolated the strongest variants."

The next step is to start producing these powerful antibodies on a large scale. Before the antibody cocktail can be produced on a large scale, its safety must be demonstrated. This is done first on laboratory animals. Van Gils hopes that testing can start early next year.

Source: https://www.levif.be/actualite/sante/de ... 00445.html

See the study: https://science.sciencemag.org/content/ ... c5902.full

[Obamot]

We should be happy about it, but it is “bad” news!