Is Germany (already) using Plaquenil (Chloroquine) against Covid-19?

[GuyGadebois]

As you can see I am still waiting for my answer .....

One more who cannot read ......

That is to say?

Since I took this for myself, suddenly I am also waiting.

[VetusLignum]

Covid: how many unnecessary deaths (and how did I get cured with hydroxychloroquine) ?!

http://jdmichel.blog.tdg.ch/archive/202 ... 05601.html

I often wonder what people really understand about what's going on. As far as I'm concerned, it's obviously a little different since it's been more than thirty years that my job has consisted in decoding research and medical practices.

For the past two weeks, I have written article after article on the Covid. The most popular of them was read by almost a million people in Switzerland and France, becoming the most consulted article in the history of Mediapart blogs. I wrote a call to Mr. Alain Berset and Mr. Mauro Poggia, respectively Federal Councilor and Geneva State Councilor, both in charge of health. Call relayed by two thousand people. In vain.

by Jean-Dominique Michel, MSc medical anthropology and public health expert, Geneva.



But what do my contemporaries really know and understand about this more shocking reality than anything I have known in my thirty-year career - and believe me, have I seen it ?! In France as in Switzerland, the political and health authorities have blood on their hands today, with hundreds of deaths on their conscience. People who for almost all of them would not have died if they had been treated in time. Instead of letting them reach desperate states, this even when we have an effective treatment, safe when given by a doctor, which lowers the viral load in a few days.

Yes, you read that right: the Swiss and French governments (and unfortunately other countries) have left hundreds of people die by depriving them of the possibility of having a simple, well-known and inexpensive treatment, which they it is imperative to give at the start of a SARS-CoV-2 infection.

What have our authorities done for more than two weeks now that the effectiveness of this treatment has been confirmed? Well, they have found nothing better than reserving the stocks of hydroxychloroquine for the hospital, making it impossible for doctors to prescribe them and keeping them for people for whom it is already too late, even though the relevant indication is to prescribe treatment before complications occur, precisely to prevent them.

Do we simply measure to say it not only the absurdity, but also the monstrosity of the thing ?!

Admittedly, controversies still exist regarding the "scientific" demonstration of the efficacy of hydroxychloroquine against Covid. But in fact, the question is not there! Doctors are able to form an opinion for themselves, and the treatment protocol developed at Méditerranée-Infection (the most important center in clinical infectious diseases in Europe, remember) is easily applicable by any of them. them.

The right to prescribe the right remedies to their patients is an inalienable right of any doctor with the benefit of a license to practice. The fact that the state, in a pandemic period, waiting without valid reason for this fundamental right of general practitioners, thereby putting their patients at risk, is a violation of which I see no other possible final destination for its officials than a criminal court.



Hydroxychloroquine from a public health perspective

Medical personalities and movements of doctors are vigorously activating to demand the immediate correction of this monstrosity, nothing works for the moment. Professor Xavier Deparis, specialist in epidemiology and public health, reveals a singular account for France, easy to extrapolate for Switzerland. It is always good to read a colleague who is competent in his work. Here is what he indicates as the 5th pillar of a set of measures to be implemented to get out of the health crisis:



“Treat the cases detected upstream to prevent them from getting worse and becoming severe cases requiring hospitalization.

Problem: treatment is needed.

Solution: the treatment with hydroxychloroquine and azithromycin seems adapted to this situation.

Provided that it is prescribed by a doctor who will monitor it, this treatment is very well tolerated and can be administered on a large scale.

The effectiveness of this treatment is disputed: some doctors say it has not been demonstrated, others say the opposite. Faced with this debate, should we or should we not use hydroxychloroquine associated with azithromycin?

To clarify our decision, let's explore this fairly realistic scenario of the COVID epidemic, on a population scale:

- When we are infected, in 99% of cases, we will either have an asymptomatic infection (that is to say that we will remain in apparent good health), or a mild condition that will heal in a few days. In 1% of cases, we will present a severe form which will require hospitalization. The risk of death will be one in six. So, out of 10 infected people, we will observe 000 asymptomatic or mild cases and 9900 severe cases, of which 100 will die (one in six: around 17%).

- For the epidemic to end, mass immunity will have to be achieved. For example, for measles, the threshold is 95%. This means that when 95% of the population is immunized against measles, the measles virus can no longer circulate in the population and cases of measles disappear or are extremely rare. In the case of COVID-19, given its fortunately less contagiousness than that of measles, it is possible to consider that a mass immunity of the order of 75% will stop the epidemic. Only a few cases or occasional foci will continue to be observed, beyond this threshold. So, for a million people exposed to COVID-19, we will count 750 contaminated people at the end of the epidemic. Of these 000 people, 750000% will have had a severe form of the disease requiring hospitalization, or 1, of which one in six will have died, or 7500.

- The advantage of treatment with hydroxychloroquine and azithromycin lies in its ability to reduce contagiousness and reduce the occurrence of severe forms, if prescribed sufficiently early, according to defined clinical criteria.

If this treatment has no capacity to prevent the occurrence of severe forms of the disease, we will not see any change.
If this treatment reduces the appearance of severe forms by 10%, then we will observe a reduction of 750 severe forms, including 125 deaths.
If this treatment reduces the appearance of severe forms by 30%, we will have prevented the occurrence of 2250 severe forms, including 375 deaths.
If this treatment reduces the appearance of severe forms by 50%, then we will observe a reduction of 3250 severe forms, including 625 deaths.

With a personal extrapolation (JDM) since the success indicated by the Marseille IHU being 90% disappearance of the viral load at 7 days:

If this treatment reduces the appearance of severe forms by 90%, then we will observe a reduction of 6250 severe forms, including 1 deaths.



The decrease in the number of severe forms will further reduce the pressure on hospital resuscitation services. This means that the remaining severe cases can be treated more effectively, hence the hope of a further reduction in lethality through a qualitative gain in the management of cases.

Who will prescribe hydroxychloroquine and azithromycin? It will be hospital doctors and general practitioners, but also, why not, occupational physicians, whose decree in preparation is already broadening the competences faced with COVID.

The implementation of treatment with hydroxychloroquine and azithromycin, if it is effective, will also be an essential pillar to facilitate the break out of containment and economic recovery. Indeed, if confinement aims to spread severe cases over time, it also has the “perverse” effect of preventing us from immunizing ourselves and therefore reaching the threshold of 75% of immunized people. To get out of confinement, resume a normal life and revive the economy without fear of an epidemic rebound, the three pillars of the strategy will be the wearing of masks and barrier measures for all, screening and early treatment! In fact, the right strategy for exiting containment will be to put in place the strategy that South Korea followed from the outset and which enabled it to avoid containment and maintain economic activity.

What is the only real risk in using hydroxychloroquine and azithromycin therapy? It is that it is not effective. In this case, we can stop it. What is its benefit? If its effectiveness is between 10% and 50%: from significant to considerable.

So why are we still waiting for its implementation in France? It is inexplicable for me, especially since more and more countries decide to use it. "



So this is the monstrous scenario in which we are: the authorities violate the freedom of doctors, and that of the population to receive the best treatment against the Covid. Worse, in France, they have just facilitated the prescription of Rivotril in nursing homes, raising the suspicion of favoring active euthanasia of the elderly. While forbidding to protect them by the association hydroxychloroquine + azithromycin, as it was magnificently beneficial to this 95 year old lady rebuilding her Covid + with respiratory complications at the Locle hospital, in Switzerland!

Scary shit, mind you!



Sick and treated

While I was working to shed some light on this pandemic from my area of ​​expertise, I was also living a singular personal adventure by being touched by the Covid myself. The anthropology knowledge methodology is participant observation: we explore a cultural or social reality the better the less we experience it. There, it was even more than partly, and of course devilishly interesting.

I hesitated to speak about it for a long time, for two reasons: the first is that I don't really like the "personalization" of health issues. My little person is obviously not interesting. On the other hand, if my experience can illustrate or make understand a particular reality, it can sometimes legitimize an exception to this modesty.

The other reason is that the anecdotal (what a particular person experiences) does not necessarily have relevance in terms of public health. These days, for example, we hear a lot of examples, obviously tragic, of children or young people who are presented as deceased from Covid. It is not a question of disputing the reality of such dramas, nor of lacking empathy for the families so terribly mourning. The reality is nonetheless: the deaths of young people (under 65) and not suffering from other pre-existing pathologies are very rare. They constitute less than 1% of all deaths. As much as it should be noted that there are such exceptions, it is important to remember that they are very thank God.

I am therefore too well placed to know that a personal experience, however convincing it may be, does not have universal value when it comes to recovery. What can give such confirmation is of course the consolidated data - as far as the Marseille treatment protocol is concerned, this consolidation is already as convincing as it is possible for any mind, even a little bit capable of epistemic sagacity.

At this stage therefore, and after having actively campaigned for the right to prescribe general practitioners, I can calmly share my experience. Mr. François Schaller, journalist who recently painted a portrait of my fight, had elegantly guessed the answer to a question he was careful not to ask me (in Paris-Match Switzerland, April 3).

So I contracted Sars-CoV-2 the week of March 9-13. When exactly ? I would be very embarrassed to say it. I had adopted (like members of my family and my professional teams) good practices of social distancing, so I literally neither kissed nor shook hands with anyone these days. On Saturday the 14th, however, I started to have chills of fever coupled with a strong headache.

From March 15, I voluntarily confined myself to a room in my apartment, now interacting remotely with my loved ones. I contacted my attending physician by telephone, who advised me to rest and possibly take a febrifuge (Dafalgan). Fever being the body's best defense response to viruses, I abstained from it as soon as my temperature never exceeded 39 ° 5.

On Wednesday, March 18, my doctor informs me that the medical center where he works has some Covid screening tests and he suggests that I come and get tested. So I land in the midst of masked medical assistants who make me wash my hands several times by handing me a mask to place on my face.

I see my doctor arriving with an outfit that makes him look like a Chinese decontaminator. He sticks a rod into my sinuses before sealing it in a test tube. We talk a little bit about the research of Méditerranée-Infection with hydroxychloroquine, which I follow closely and of which he has also heard.

The same day I start writing my text “Covid-19: end of the game ?! I am so motivated that I write this long text in one night, with more than 39 ° fever. The brain vitality and cognitive performance strategies that I developed with my colleagues at the BrainFIT Institute are once again proving their worth, and I obviously know my subject. In a few hours, the text is finalized.

I am sincerely convinced that it will have no success: it is much too long, it gives a divergent point of view on the pandemic and presents a perspective (that of medical anthropology) which remains little known, even if it is as relevant as it can be for this topic. Sending him the following day at random to the editor of an excellent daily newspaper, he replied quickly: “Hello and thank you. Interesting, but gigantic and with too many ideas, it goes in all directions. In one sentence, your central point would be ....? "To which I offer myself the luxury of answering:" In one sentence: If it is too short is it stupid ?! It was not for publication anyway ... thanks for your message and best regards! I don't hold it against him and he doesn't mind: he's a really good journalist.



Diagnostic

My doctor calls me the next day, Thursday March 19, to confirm the diagnosis: I am indeed Covid +. We discuss for a long time and I share with him my conviction that until proof to the contrary, the infection being benign for the immense majority of people, I do not fear any particular risk concerning me (I am on the whole in healthy). To which I add that I would however like to have the assurance in the event of aggravation of being able to have the treatment protocol developed in Marseille. We are not yet addressing the issue of Plaquenil, but my doctor agrees to prescribe azithromycin in reserve, this antibiotic, moreover, with an antiviral action included in the Marseille protocol.

I continue my snowman, always with fever and headaches, remaining active in the production of different items to cover the current sanitary junk. I receive hundreds of emails in response to my writings, almost all positive and full of encouragement which of course makes me feel good.

I am also in contact with an acquaintance at the hospital, a doctor working in the emergency room. He critically follows my analyzes and proposals, drawing my attention to what he experiences with his colleagues day after day. He also asks me questions about my condition, which affects me - a doctor is always a doctor and I like their concern for others. In particular, he tells me to monitor my breathing, inviting me to take 40 steps in my apartment (in fact I live in one room!) And to check if it is short of breath.

Tuesday, March 24, things are getting worse: I am on my 10th day of Covid, and I feel indeed a respiratory discomfort appear. I have sufficiently studied the medial literature available on the Covid to know that such an aggravation is really not a good sign. It is indeed a recognized threshold, and if things deteriorate from there, it can very quickly go in the wrong direction.

I call my doctor back and express my concern. I share with him my feeling that this beginning of aggravation gives us a 48h shooting window to start the hydroxychloroquine + azithromycin treatment. But that if we miss this chance, I may find myself caught in the slide leading to intensive care with no way of acting.

I obviously fear that despite the solidity of my arguments and his integrity as a doctor, he dares not take the step of prescribing a treatment "outside the usual indications" and which continues to be the subject of many denigration and mistrust on the part of the health authorities.

"I'm aware of putting pressure on you," I told him, and I apologize. But I am also convinced that it is possible to be so from what I am saying and I ask you to agree to accompany me on this path. He wants to send me to do a lung scan, which has meanwhile become complicated since only the HUG (Geneva university hospitals) still perform this examination for Covid + patients.

I ask him for one more act of faith: "If I go to HUG, I will be taken in the care sector while the treatment that I ask you has the function of curing the viral load in a way that prevents development of any problem. Whether I already have lung damage or not, the treatment will take care of it. To my relief, my doctor responded to my request. We review together the points to check (drug interactions, absence of personal and family cardiac history) and he delivers me the precious prescription for hydroxychloroquine (Plaquenil).

I am so relieved and so positively admiring my doctor! He has this mixture of humility and skill that make them the greatest. A man who, moreover, for thirty years has been providing a local medical center for two half-days a week, welcoming all comers for these consultations which constitute the authentic heart of medicine. Her courage, daring and taking responsibility to step over the line when I feel I need it comfort me and fill me with gratitude.

I call the pharmacy to check that they have received my doctor's fax and see how to organize the delivery. "Ah, but we can no longer deliver this drug, sir, it is placed in hospital reserve! I hear myself answering the phone. I obviously invoke the Hippocratic oath and the scandalous side of this prohibition, nothing helps.



Prohibition!

No pharmacy in Switzerland has the right to honor my doctor's prescription. Which aims to protect me from all unpleasant surprises when, infected with the Covid for ten days, my breathing is getting worse! Message from the authorities: "Decline in peace if this is your destiny and we will take you all howling sirens towards a bed of misery where we will intubate you if you need to." But protect yourself with a treatment prescribed by your doctor, you don't think about it, we forbid you! "

Technically, the authorities hide behind the need to manage stocks well and ensure the supply of patients who already need this medicine. Noble reasons, badly masking this other concomitant reality: the authorities refuse the offer of pharmas to produce mountains of Plaquenil quickly. And reserve the use in the hospital, prescribing it only for the most serious cases, that is to say when it is too late according to Méditerranée-Infection to obtain the beneficial effect of the treatment. How do you say "stupid" in federal French ?!

Obviously, it is not the fact of lugging around with this or that brand of watch on your wrist that makes you do pretty well at my age. It's good to have accumulated enough life experience to be at least a bit street-smart. I will resolve my supply of Plaquenil by quickly and effectively organizing an illegal transaction, at the edge of a parking lot, during which my wife was given a precious box of the precious medicine. Passed from hand to hand, in hiding, like a prohibited substance. A remedy perhaps vital for my health !!! A reader will whisper to me the qualifier I was missing: it's just sordid.



Neat and treated

I start the treatment on Wednesday 25 in the evening. The next two days, my breath continues to shorten. Frankly, it's pretty scary. A long experience of body work and in particular breathing exercises (pranayama and apnea are part of the practices that I have explored) allow me to calm anxiety and self-regulate my saturation in blood oxygen.

The night from Friday to Saturday March 28 is particularly painful. I cough a lot, run out of breath quickly, and start to worry that I started treatment too late. My friend from the hospital takes news, then invites me to call the ambulance for a possible transfer. I do not feel in danger of acute respiratory distress but do not rule out at this stage the need for increased oxygenation. The ambulance arrives at the bottom of my building and I go down on my own, with a protective mask on my face.

I am greeted with great humanity by two paramedics who decontaminate me by smartphone while they ask me questions. I will find out soon after, my friend, a doctor at the hospital, and a colleague are watching me to assess me. The verdict falls: no need for hospitalization at this stage, they suggest I go home. What I do to the relief of my wife and my daughter, a little worried of course at the idea of ​​seeing me leave without a scheduled return date.

From there, things improve quickly. The next day, shortness of breath disappears, giving way to a fairly strong but bearable cough. Which will also disappear in 24 hours. In short, three days later, on the 6th day of the hydroxychloroquine + azithromycin treatment, the symptoms disappear, I regain my appetite, and like thousands of people who have benefited from the same treatment as me, I find myself out of business.



Now what?!

Following, loyal readers of this blog know it. I decipher with ease - as they seem obvious to me - the relevance but also the epistemological approach underlying the work of Professor Raoult and his teams. I also decipher as much as I can the serious manipulations implemented by the French government and the pseudoscientific authorities. I am active so much and more to understand the criminal logic at work, making sure to make unavailable the only treatment currently effective against Covid, at the cost of thousands of lives!

Of course, I could selfishly settle for getting this treatment when I needed it. But above all, this privilege constitutes one more injustice, which offends me and revolts me. Even if I have never "made a career" (we laugh on social networks it seems from this "Swiss expert without Wikipedia notice"), the reason why I always kept away from institutions has resided in my determination to keep complete freedom of thought and speech.

I have often been invited to share my work and the fruit of my research, in settings as prestigious as one can dream of, with the benevolent confidence of luminaries in their fields. Like Professor Guy Dubreuil, founder of the Department of Anthropology at the University of Montreal and pioneer of ethnopsychology; Professor Luc Chabot, initiator of innovative community training programs at the University of Montreal as well; Professor Ilario Rossi, one of the very best health anthropologists, at the University of Lausanne; Professor Jacques Hainard, director of the Geneva Museum of Ethnography; Professor François Ferrero, pioneer of community and social psychiatry at the Faculty of Medicine at the University of Geneva and former chief physician of adult psychiatry; Prof. Stéphane Rossini, academic reference in matters of action and social policy; or Pr Jacques Besson, professor emeritus of psychiatry at the University of Lausanne and one of the great world pioneers of research on the links between spirituality and health.

Even if I remain a modest specialist with some successes of esteem in my professional field, I am still in a privileged position which made it easy for me (helped by an exceptional doctor and secret accomplices) to obtain the saving treatment which I needed.

Let’s speak French: any minister, deputy, senior official, doctor, researcher or privileged person who would need it would easily find the necessary resources to be prescribed this same treatment. The scandalous decisions of the French and Swiss governments ultimately only target “people who are nothing” to speak like Emmanuel Macron, the “beggars”, the “toothless”, the “voiceless”, the “Mr. and Mrs. Everyone ”, those who are asked to shut their mouths and let the rulers shamefully put them in danger. Those to whom I have devoted my professional life because I have always found in those "watched from above" and "people in a situation of social precariousness or psychic otherness" treasures of humility and kindness that are usually scarce among the ruling elites.

The calls are multiplying, for the moment nothing helps: the Swiss and French governments let die their fellow citizens by hundreds or by thousands rather than making available to the general practitioners an effective treatment. Criminal decision, which will logically end before a criminal court. As lawyer Régis de Castelnau writes in the weekly Marianne: “The appearance of those responsible before the criminal judge is inevitable. "

Professor Perronne says: “We are now 500 dead a day. How many thousands of deaths will this government have on our conscience? But who advises them? It's revolting. "

In Switzerland and Geneva, how can we make MM. Berset and Poggia, badly advised in this case ?!

[Christophe]

Shhh VetusLignum it doesn't work! THOSE who decide in France know that it does not work - well rather they "grow" ....

But a medical resistance begins to be made, seen this morning at Morandini: health-pollution-prevention / resignation-of-dr-raoult-supporter-of-chloroquine-from-scientific-advice-covid19-t16370-260.html # p389847

[Christophe]

New effective molecule TOCILIZUMAB on SERIOUS cases?

Interestingly, it is also made for polyarthritis like Plaquenil ...

TOCILIZUMAB, A NEW HOPE TO FIGHT THE MOST SERIOUS FORMS

The molecule, prescribed for rheumatoid arthritis, could be effective in treating the cases of Covid-19 of greatest concern, for which there is currently no treatment.

While the "Raoult method" recommends hydroxychloroquine for ...

https://www.humanite.fr/le-tocilizumab- ... ves-687361

[thibr]

a little self-criticism and humility in the forecasts ...

[Adrien (ex-nico239)]

a little self-criticism and humility in the forecasts ...

So he chose the right example to start ...

Just with the history of the masks the WHO was ridiculed just like all those who listened to it ... fortunately not all

Coronavirus: flip-flops on masks
https://www.sciencesetavenir.fr/sante/c ... ues_143202

And you will see that soon the WHO will recommend wearing a mask .... or even make it mandatory to go out as this will become the case in France.

[izentrop]

Just with the history of the masks the WHO was ridiculed just like all those who listened to it ... fortunately not all
Coronavirus: flip-flops on masks
https://www.sciencesetavenir.fr/sante/c ... ues_143202

Yes, surprising that they realize late that a postilion can briskly cross the barrier of the symbolic meter, at least with the wind behind them.

But we suspect that "the virus may spread when people are just talking, rather than just sneezing or coughingWell-respected American scholar Anthony Fauci, adviser to Donald Trump, told Fox News on Friday.

If confirmed, this mode of transmission would explain the high contagiousness of the virus, also transmitted by patients without symptoms.

It is by integrating this possibility that the American health authorities recommended the wearing of the mask.

Previously, New York had already taken the plunge: Mayor Bill de Blasio asked residents on Thursday to cover their faces when they go out.

"It could be a scarf, something you made, a bandana, "he asserted..

Wearing a mask should be mandatory for those who are zozotating

They have understood this well and plaquenil is the least of their concerns, they fear more for their survival that they will not be able to work any more than the virus.
https://www.sciencesetavenir.fr/sante/l ... -19_143014

[Ahmed]

Izy, please make an syntax effort, otherwise it will quickly become incomprehensible; I note this sentence:

... they fear more for their survival that they will no longer be able to work than the virus.

It's good to keep it short, but not in spite of common sense ...
Good prince, I translate:

... they fear more for their survival because they can no longer work than because of the virus.

[perseus]

Hello,

An ITW from a Korean researcher that sums it up well. (it is subtitled).
And then it's calm, factual, humble.

(edit): a small article
https://www.heidi.news/sante/hydroxychl ... ma-y-croit

[perseus]

Hello,

When I think about it and by dint of looking at the publications and scientific prepub that are coming out (the inflation rate of the publications is still incredible, by the way). I am becoming quite skeptical about the possibility of finding an effective treatment (that is to say, that treats patients) in the short term among the various molecules considered.


- The countries affected on the front line have worked or tested a little in advance, we cannot say when we look at the feedback from scientists that there is - at the time of writing - favor of treatment. Hopes seem tilted in favor of: Remsdesivir, faviparir, use of plasma by healed people, chloroquine and derivatives.
- We should start to have the results of the Discovery test, the fact that it is dragging seems ominous for all of the modalities, but I hope I am wrong.
- The protocol of the IHU, is presented as rather to be taken early as soon as the positive test, it treats especially people in fairly good health but would hardly help those who have causes of comorbidity (most of the victims). It is very cumbersome to set up.

I must be in a pessimistic mood today. : s