#Covid variants (Delta, Epsilon, Lambda ...): appearance, contagion, danger, immunity, treatments, vaccines ...

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Christophe
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#Covid variants (Delta, Epsilon, Lambda ...): appearance, contagion, danger, immunity, treatments, vaccines ...




by Christophe » 26/01/21, 11:10

Since mutations can lead to new pandemic according to some specialists I am creating this new subject to take stock of the genetic evolutions and the impact of these variants ...

We had already published the phylogenetic trees here: natural-human-catastrophes / coronavirus-la-fault-à-qui-ou-a-quoi-et-raison-t16346.html

What impacts on pandemics (cases, severe cases, death) ... we already know that the English variant is 70% more contagious and 30% more fatal ... What would a variant² be (a variant can be stronger or weaker? : and outside the lab we only hear about the strongest ...) ???? How should treatments evolve? Will the vaccine efficacy (already not terrible) be compromised?

Edit addition July 2021: you will find here a synthesis and analyzes of the UK government on the variants at the end of June 2021

Excerpt:

Image


English variant: "the equivalent of a second pandemic"?

Jean-François Delfraissy indicated last night that the emergence of new variants (English, South African, Brazilian, Japanese, German and Californian) "completely change the situation". The British mutation could even lead to "the equivalent of a second pandemic" according to the President of the Scientific Council.

Variants: a critical situation

The week will be "critical" declared the chairman of the board Jean-François Delfraissy. "If we continue without doing anything more, we will be in an extremely difficult situation from mid-March," he warns. He points out that “The variants have been a game-changer for three weeks. They appear in multiple ways, have higher transmission factors, and accelerate transmission ”. While the English variant represents 7 to 9% in the Paris region, “there will be 12%, 14%, 15% of the British variant in the coming weeks […] if we continue” affirms the president. For the South African variant, it is "maybe already around 1%". The Brazilian variant is also close, since we “have an entry point with Guyana”.

In terms of the number of contaminations, France is well below that before the 2nd containment and seems suitable. However, Dr Delfraissy encourages us to "change our software" because it is "a false security", which "will not be able to last". "It's the equivalent of a second pandemic, this [British] variant." To reverse this epidemic trend, he believes that it is necessary to adapt the next February holidays, by grouping the zones and adding a week.

What impact on vaccines?

These variants could lead to a modification of the strategy put in place: "Are these variants sensitive to vaccines?" We have a response element for the English variant, it appears, with preliminary data, that it is sensitive to both Messenger RNA vaccines ».

Concerning South African and Brazilian mutations, they could oppose a stronger resistance to immunizations : "On the other hand, the variant South African and the Brazilian variant, are only slightly neutralized, both by monoclonal antibodies, which generally neutralize the virus, and are not neutralized by antibodies from patients who have already had a Covid, so there has no protection. And finally in the first data, an American study shows that on the South African variant, there is a decrease in the effectiveness of vaccines of about 40% ”Reveals Jean-François Delfraissy.

Only the Moderna vaccine would be effective against the new English and South African variants, according to the pharmaceutical group Moderna Inc. It “protects against the variants detected on this date”, by producing antibodies which neutralize these mutations. However, the company indicated that a study for an additional dose was underway to increase neutralization.


https://www.passeportsante.net/fr/Actua ... e-pandemie
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Re: Covid: Sars-Cov2 mutations and variants, evolution, immunity, treatments, vaccines?




by sen-no-sen » 26/01/21, 12:27

The use of the term variant reminds me of a sketch of strangers on marketing: an anxiety-inducing name ... but not too much.
Mutant strain this is scary, while "variant" is more seller.
Because after all, we have to conceptualize a second pandemic ...
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Re: Covid: Sars-Cov2 mutations and variants, evolution, immunity, treatments, vaccines?




by Christophe » 26/01/21, 13:47

Imagine that I asked myself the same question ... The X-Men have been there! : Mrgreen:

Then GMO and mutant, it's not far ...

All this still goes in the direction of the society "formally clean but fundamentally villainous" ... : Evil:
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Re: Covid: Sars-Cov2 mutations and variants, evolution, immunity, treatments, vaccines?




by Christophe » 26/02/21, 09:33

And one more variant, one!

this mutation, called B.1.526, first appeared in November, as evidenced by samples analyzed in the laboratory. This variant is considered for the moment as "worrying" by the researchers: it could weaken the effectiveness of the vaccines.

https://www.rtbf.be/info/monde/detail_u ... d=10706438

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Re: Covid: Sars-Cov2 mutations and variants, evolution, immunity, treatments, vaccines?




by Janic » 26/02/21, 16:31

a real laying hen this covid, he gives birth to them every day!
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Re: Covid: Sars-Cov2 mutations and variants, evolution, immunity, treatments, vaccines?




by GuyGadeboisTheBack » 26/02/21, 16:38

Janic wrote:a real laying hen this covid, he gives birth to them every day!

United States Fully Authorizes Use of Remdesivir ... (October 22, 2020)
Gilead announced that it had received authorization for the drug, under the Veklury brand, stressing that it was the only specific treatment against COVID-19 so authorized after a more rigorous and definitive verification procedure.

https://www.lapresse.ca/international/e ... esivir.php
I'm laughing, but I'm laughing ... : Mrgreen:
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Re: Covid: Sars-Cov2 mutations and variants, evolution, immunity, treatments, vaccines?




by Janic » 26/02/21, 18:46

I'm laughing, but I'm laughing ... : Mrgreen:
and the populations are fed up, fed up, fed up! : Cry:
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Re: Covid: Sars-Cov2 mutations and variants, evolution, immunity, treatments, vaccines?




by Christophe » 01/03/21, 10:49

GuyGadeboisLeRetour wrote:
Janic wrote:a real laying hen this covid, he gives birth to them every day!

United States Fully Authorizes Use of Remdesivir ... (October 22, 2020)
Gilead announced that it had received authorization for the drug, under the Veklury brand, stressing that it was the only specific treatment against COVID-19 so authorized after a more rigorous and definitive verification procedure.

https://www.lapresse.ca/international/e ... esivir.php
I'm laughing, but I'm laughing ... : Mrgreen:


I don't really see the connection with the changes but mouahahah who knows? Can it be effective against variants? It is not yet taxed to dream! : Mrgreen:

We didn't get our ass out of the brambles!
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Re: Covid: Sars-Cov2 mutations and variants, evolution, immunity, treatments, vaccines?




by GuyGadeboisTheBack » 01/03/21, 12:00

Christophe wrote:I don't really see the connection with the changes but mouahahah who knows? Can it be effective against variants? It is not yet taxed to dream! : Mrgreen:

Verluky, it's Remdesivir ... that's the connection with mutations.
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