The saliva of a tick to cure cancer

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The saliva of a tick to cure cancer

by recyclinage » 29/08/09, 12:27

The saliva of a tick, hope of Brazilian researchers to cure cancer

From Marc BURLEIGH (AFP) - 16 hours ago

SAO PAULO - The tick does not only transmit infectious diseases: its saliva also contains a protein that could cure cancers of the skin, liver and pancreas, according to Brazilian researchers.

By studying a South American specimen of this blood-sucking parasite, Amblyomma cajennense, they discovered that this Photoprotein destroys cancer cells while sparing healthy cells.

"This is a major discovery," said the director of this study, Ana Marisa Chudzinski-Tavassi, researcher in molecular biology at the Butantan Institute in Sao Paulo.

"The substance in the saliva of this tick ... could be the cure for cancer," she told AFP.

The researcher says she accidentally discovered the virtues of this protein, called Active Factor X, by testing the anti-coagulant properties of tick saliva, which allow the parasite to gorse itself on the blood of animals or humans to which it is attached. 'attack.

The protein has common characteristics with a widespread anti-coagulant called TFPI, or Kunitz inhibitor, which also acts on cell growth.

Lab tests were then conducted to see if the protein produced effects on the cancer cells and their results exceeded all researchers' expectations.

"To our surprise, it did not kill the healthy cells, which were also tested," says Ms. Chudzinski-Tavassi. "But it killed the cancer cells that were analyzed."

In her modest laboratory of the institute, with decrepit walls, the researcher collects saliva from ticks by placing straws under their heads.

The few drops thus collected are then reproduced in yeast tanks to carry out tests on cancer laboratory rats.

The results are more than promising.

"If I treat a small tumor from an animal daily for 14 days, this tumor does not grow and even shrinks. The tumor mass shrinks. And if you treat it for 42 days, the tumor disappears completely," explains the researcher.

To produce a drug, however, will require years of clinical testing and large investments, two things that Brazil can not provide at the moment.

"Making a discovery is one thing. Turning it into medicine is another totally different," regrets Ms. Chudzinski-Tavassi.

In the meantime, she has filed a patent application for the protein of this tick and travels the world to present his discovery, which has also been the subject of publications in medical journals.

Copyright © AFP 2009. All rights reserved.

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by Obamot » 29/08/09, 12:51

Good news.

It is doubtful, however, that such a molecule alone is enough to restore health. Another researcher (Lausanne laureate) also discovered that "the body develop cancers because he would "need" them ". That this disease was a kind of "last resort" of the body before the point of no return.

Anyway it would be better to tackle the causes of diseases rather than treating the effects ... which does not mean that we should not treat the effects ... : Mrgreen: Because knowing a little bit about the "stubborn" side of human nature ... if we had to wait on patients to change their way of life ...
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by elephant » 29/08/09, 14:45

I am always amazed by the ridiculously low amounts with which biochemists can work.

And what saw me the most is the enzyme replicators of DNA.

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