Advances in the fight against the coronavirus

[Obamot]

A new study on vitamin D
https://www.sciencedirect.com/science/a ... 602030296X

And a good video:
https://www.youtube.com/watch?v=9UdsrvTyKfw

He's right, big doses of vitamin D every week (sometimes prescribed once a month = “mega-dose”) exhaust us.

This video is very good. It would take several, because let's never forget that health does not revolve around the intake of vitamin D alone - for a favorable acid / base balance to take hold! For the metabolisms: calcium, fats and sugar (and many others) to take place, complex biochemical (and bioelectronic) combinations are needed and the inputs required for these reactions to take place. .. in general we can note efficiency (among the most common) in lives. A, B12 (+ B complex), C, D, E, F (polyunsaturated fatty acids Omega-3 -6 -9) iron, magnesium, selenium, zinc ... And also not too much, do not drink too much water mineralized (the minerals they contain can put our cells close to a “short-circuit” during assimilation and they are of little use to the cells, since they are not bio-available)

This is why, if we do the test for vitamin D, we might as well do a complete biocheck that will tell everything - the 1st difficulty is finding a doctor at the cutting edge, able to interpret the results - and as a lab (that helps) choose Unilab, they give explanatory tables for each of the efficiency discovered is what to eat to fill them / compensate with a list of suggested foods (or an equivalent lab that will do the same and affordable, it's already expensive , but there is much more expensive)

[Christophe]

Reminders on the 6 cases of covid identified by their symptoms: https://www.medrxiv.org/content/10.1101 ... 20129056v1

The six forms of Covid-19:

1 Flu-like without fever: Headache, loss of smell, cough, sore throat and pain, but no fever.

2 Flu-like with fever: Similar to group 1, plus loss of appetite and fever.

3 Gastrointestinal type: Diarrhea, loss of smell and appetite, headache, sore throat, chest pain. Usually no cough.

4 Fatigue type: Fatigue, headache, loss of smell, cough, chest pain and fever. This group is considered more serious than the previous three, as 8,6% of them need respiratory support.

5 Confusion type: People experience confusion in addition to the symptoms listed in the fourth group. About 10% of them will need respiratory assistance.

6 Abdominal and respiratory type: Considered to be the most serious group, as almost half of people will need to be hospitalized and about a fifth will need respiratory assistance. Symptoms include headache, fever, loss of smell and appetite, cough, sore throat, chest pain, as well as shortness of breath, diarrhea and abdominal pain, muscle pain, confusion, and fatigue.

[Christophe]

[Adrien (ex-nico239)]

Another


Chinese Researchers Develop & Share AI Model that Can Diagnose COVID-19 over Influenza & Pneumonia in 3 Seconds

Researchers at Tsinghua University and Wuhan-based Union Hospital (associated with Huazhong University of Science and Technology) have developed an artificial intelligence (AI) -based system that increases doctors' detection of COVID-19 from other viruses such as influenza or other respiratory illnesses. in as little as three seconds. Recently published in the journal Nature Communications, this investigative tool has great potential to help suppliers differentiate between SARS-CoV-2, the virus that causes COVID-19, and influenza as it approaches. flu season and the next wave of COVID-19 is sweeping through large parts of the world. This system can help medical providers almost immediately differentiate COVID-19 from other diseases with great precision by identifying deltas in patients' CT scans. In the spirit of the global collaboration targeting COVID-19, the researchers shared the data behind the research as well as the code for the AI ​​system in GitHub.

[Christophe]

Ah well it will be useful this winter (and the following ones?) ... if the Chinese have time to put it on the market by then?

[Adrien (ex-nico239)]

The side effects of Remdesivir studied by French researchers.

Hepatic Disorders With the Use of Remdesivir for Coronavirus 2019

We found 387 reports with remdesivir registered in VigiBase, of which 130 hepatic adverse reactions (34%) were reported. Reports came from the United States (87) and Europe (43), mainly involving men (81, 62%), with an average age of 54,9 years (minimum 2, maximum 92). The duration of treatment with remdesivir ranged from 1 day (15 stops for serious side effects) to 11 days, with an average duration of 3,8 days. In the majority of cases (122, 94%), remdesivir was the only drug suspected. Most cases were severe (94, 72%) (i.e. resulting in hospitalization or extended hospital stay). The mean time to onset of liver problems was 5,4 days. Increased liver enzymes were the most frequently reported adverse reactions (114, 88%), involving liver transaminases (aspartate transaminase and alanine transaminase) in 79 cases (61%) and bilirubin in 4 cases (3%) . Other cases have been reported such as liver failure or hepatitis. Compared with hydroxychloroquine, lopinavir / ritonavir or tocilizumab, the use of remdesivir has been associated with an increased risk of reporting hepatic disorders (MMR, 1,94; 95% CI, 1,54–2,45, 1) (Table 1,60). When we limited the analysis to tocilizumab users (reference group), the MMR remained significant (95; 1,13% CI, 2,27–XNUMX).

[VetusLignum]

Melatonin, much more effective than dexamethasone on intubated patients.
https://www.medrxiv.org/content/10.1101 ... 1.full.pdf

2020.10.15.20213546v1.full.pdf

(3.08 million) Downloaded times 634

[izentrop]

In short:

Solidarity: the totality of the results of the study with regard to the branch "antivirals" fell.
The result is clear: NOTHING works. While Remdesivir has a slight effect on the length of hospital stay, it does not reduce mortality, nor does interferon or Lopinavir. Not surprisingly, hydroxychloroquine, it worsens the condition of patients.
The results are available here: https://www.medrxiv.org/content/10.1101 ... 20209817v1

Airportage: after months of doubts on this subject, the CDC seems to have decided. The virus is in the vast majority of cases transported by droplets of saliva but can, in the case of a closed unventilated room which has contained a sick person and a healthy person for a long time, be airborne. New guidelines taking this aspect into account have been published here: https://www.cdc.gov/coronavirus/2019-nc ... reads.html

a study published in Immunity (and available here: https://www.cell.com/immunity/fulltext/S1074-7613(20) 30445-3 ...) tends to show that immunity (in any case natural immunity, see section “Method point of the week”) only lasts 5 to 7 months. If you do the math, that means that from now on, the patients of the first wave who caught it in early March can have it again. If this data is confirmed, all strategies aimed at seeking group immunity in the population by non-medical means are simply doomed to failure.

Europe: it's not just here that it beats. In Switzerland, the wearing of a mask is now compulsory in all closed public places, gatherings of more than 15 people in public spaces are prohibited, private demonstrations of more than 15 people are highly regulated (hear that you may get a waiver for funeral but you can sit on your wedding) and telecommuting recommended, in order to contain a large rebound of cases. The Czech Republic, relatively untouched by the first wave, finds itself building a field hospital on the outskirts of Prague to cope with what is currently the highest rate of death per inhabitants of the continent. In Poland, schools, colleges and high schools are closing one after the other, bars and restaurants must close at 21 p.m., wedding ceremonies are prohibited until further notice and the number of people is limited for shops, transport and offices religious. In the UK, the most bereaved country in Europe, indoor meetings are prohibited between friends and relatives from different homes in several areas for a total of 11 million people concerned. ...
https://www.facebook.com/groups/697055387583783

[Christophe]

Good summary, thank you Izy

You could just have added that wearing a mask seems to decrease the severity of cases as well ... I don't know if we already have double "blind" studies on it ... they would not be very correct ethically but there are enough of "real" cases to be able to decide I think ...

[izentrop]

Good summary, thank you Izy
You could just have added that wearing a mask seems to decrease the severity of cases as well ... I don't know if we already have double "blind" studies on it ... they would not be very correct ethically but there are enough of "real" cases to be able to decide I think ...

You're right, on this subject there are several observational studies and we already knew in the case of other viral infections that there was a correlation between inoculum and severity of the disease.

I did not give the correct link in the summary, here it is:


There is also good news of the week, BFMTV is committed to no longer invite "reassurance" who tamper with data, such as Raoult, Perrone, Toussaint and Toubiana